Dr Papa Kwasi Nduom, the flagbearer of the Progressive People's Party (PPP), has called for the May 25 African Union holiday to be scrapped.
In a Facebook post on Wednesday, Dr Nduom said he supported commemorating the day to remember those who fought for Africa's liberation and independence and to think through what must be done to guarantee African people a high quality of life.
However, he said, there was the need to work for stronger institutions and good economies across the continent and prosperity for the people, something he said would not be achieved through "holiday upon holiday".
"We lose productivity and reduce the opportunity to become competitive nations this way," he said, stressing that the holiday should be scrapped.
"This will be on my hit list as the President of the Republic of Ghana," he added.