The Europa League draws have been held and interesting fixtures were drawn and the two top Premier League sides will have been given tricky tests in the next round.
North London club, Arsenal will take on Belorussian side, Bate Borisov in their round of 32 match over two legs in February.
Chelsea will also test their ambitions against Swedish side Malmo while Sevilla will lock horns with Serie A side Lazio.
Carlo Ancelotti's Napoli will be guest to Swiss side FC Zurich and Luciano Spalletti's Inter Milan and Austrian side Rapid Vienna are set for a showdown.
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Scottish champions Celtic will have the most difficult test in their intercontinental campaign against Champions League drop-out Valencia.
Two eliminated Champions League sides Benfica and Galatasary will square up against each other as well as Gent taking on Russian side Zenith St. Petersbrugh.
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Below is a comprehensive list of the round of 32 matches in the Europa League
Stade Rennais vs Betis
Olympiacos vs Dynamo Kyiv
Lazio vs Sevilla
Fenerbahce vs Zenit
Sporting CP vs Villarreal
BATE vs Arsenal
Galatasaray vs Benfica
Viktoria Plzeň vs Dinamo Zagreb
Club Brugge vs Salzburg
Rapid Wien vs Inter
Slavia Praha vs Genk
Krasnodar vs Leverkusen
FC Zürich vs Napoli
Malmö vs Chelsea
Shakhtar Donetsk vs Eintracht Frankfurt
Celtic vs Valencia