Best blood group compatibility for marriage and pregnancy

Best blood group compatibility for marriage and pregnancy

Besides love, blood group compatibility between spouses is another crucial thing to consider before consenting to marriage. Although this does not affect one's ability to have and maintain a happy, healthy marriage, it is essential when planning to have children. So, what is the best blood group compatibility for marriage?

Best blood group compatibility for marriage
A chart showing the degree of risk. Image: @bloodtype
Source: UGC

A difference in blood groups of partners in a marriage is not a happiness killer. However, awareness of this helps make an informed decision regarding the recommended medical approaches towards bearing children without genetic anomalies.

Blood types

It is a good practice to know the plasma group of one's partner in case of an emergency. There are four major blood group types, and everyone falls under one of these plasma types with variations in the groups. These include:

  • A
  • B
  • O
  • AB

Usually, these groups vary based on the absence or presence of antigens, which are responsible for stimulating the immune response in a person.

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Besides, there is another element that comes to play. The Rhesus factors (Rh factor) denoted by '+' for presence and '-' absence also affect one's grouping. With this in mind, blood groups double in number to eight as follows:

  • A+
  • B+
  • O+
  • AB+
  • A-
  • B-
  • O-
  • AB-

Worthy of note is that everyone is born with the plasma type they possess, and no medical procedure can change this later in life. By implication, someone born with blood group B positive, for instance, can not change to something else in their entire life.

Does blood compatibility affect pregnancy?

Because of the Rh factor, there are some blood types that are not compatible for pregnancy. The Rh factor is an inherited protein, meaning that they get it from their parents and pass it to their children.

Although being Rh positive or negative does not impact a person's health as a person, it can affect youth pregnancy.

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Biological mothers may become concerned with the Rh factor if the mother is Rh- and the baby is Rh+. This is because blood cells from an Rh+ baby crossing its Rh- mother’s bloodstream might trigger an immune response.

Best blood group compatibility for marriage
Red blood cell compatibility table. Photo: @bloodtype
Source: UGC

More so, the mother’s body might form antibodies to attack the baby’s Rh+ red blood cells. For instance, a blood group A positive child will have their immune system attacked by the antibodies formed by the mother’s Rh- cells as a defence measure.

With this understanding, the doctor suggests a blood type and Rh factor screening at the first visit during prenatal. If a mother is an A+ blood group, the doctor will further conduct a test to determine the child's Rh.

He/she will also test if the pregnant mother's body has formed antibodies to fight the child's body cells.

Although there is no blood exchange between a mother and the child during pregnancy, there is a high risk during delivery. In blood group compatibility issues due to Rh presence, the plasma will form antibodies to fight that of the child.

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Usually, there are no problems that arise during the first pregnancy; the antibodies formed during the first pregnancy will hardly affect the child. A problem arises with subsequent pregnancies.

Suppose the first pregnancy has Rh incompatibility with the child, and the subsequent pregnancies had the same problem.

In that case, there is a likelihood that the antibodies formed will damage the child's body cells. The doctor will have to prescribe a medical procedure that will help protect the child.

What blood types should not have babies together?

Usually, it is not advisable for a man and a woman whose Rh factors are not the same to have babies. This often leads to Rh incompatibility, which can cause jaundice for a child.

A child has jaundice when there's bilirubin, a buildup of an orangish-red substance in the blood. This is produced when red blood cells break down naturally.

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Nevertheless, it is not every child with Rh incompatibility that will develop jaundice. At the same time, not every baby with jaundice will require extensive treatment. What determines this is how much bilirubin collects in the baby's blood.

Types of genotype

The genotype is a description of the pair of alleles. Conventionally, the three different alleles make a total of six genotypes. These genotypes include:

  • AA
  • AO
  • BB
  • BO
  • AB
  • OO

A plasma test is used in determining the presence of A or B characteristics in human plasma. However, it is impossible to determine the exact genotype in a human body using one plasma test.

For instance, in a person with blood type A, at least one copy of the A allele is present. However, further tests may reveal two copies, thereby giving them an AA genotype.

Therefore, someone with plasma group A may have a genotype AA or AO. Similarly, someone with plasma group B will have either genotype BB or BO.

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Sickle cell and marriage compatibility

One of the biggest problems to avoid for any couple is sickle cell types and marriage. Whereas most people will stick to the physical outlook (phenotype), a person’s genetic characteristics are more vital.

Human genotypes are AA, AS, AC, and SS. These combinations refer to the constituents of haemoglobin gene found in red plasma cells. AC is a rare type, but AS and AC indicate an abnormality. Check out the genotype compatibility chart:

Which blood group is the best
Image: @bloodtype
Source: UGC

The following is worthy of note:

  • AA + AA = AA, AA, AA, AA (excellent)
  • AA + AS = AA, AS, AA, AS, (good)
  • AA + SS = AS, AS, AS, AS, (fair)
  • AA + AC = AA, AA, AA, AC. (good)
  • AS + AS = AA, AS, AS, SS, (very bad)
  • AS + SS = AS, SS, SS, SS, (very bad)
  • AS + AC = AA, AC, AS,SS. (bad; advice needed)
  • SS + SS = SS, SS, SS, SS, (very bad)
  • AC + SS = AS, AS, SS, SS, (very bad)
  • AC + AC = AA, AC, AC, SS. (bad; advice needed)

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Blood type compatibility for love

Every blood group is perfect in its natural sense. Yet, the ones considered better in transfusion include AB and O. While the former is a universal receiver, the latter is a universal donor.

However, a person with an O+ blood group cannot transfuse to an O- person because of the Rh incompatibility. Nevertheless, a person with this blood type can transfuse to another with a B-positive blood group or an A+ person.

So, with the understanding of the blood group matching table, can O+ blood group marry A+? Yes. O+ is considered the most needed blood type, and patients even get it more than any other blood type.

Although O+ red blood cells are not universally compatible with all types, they are compatible with positive red blood cells (A+, B+, O+, AB+).

According to the blood group compatibility chart, the best genotypes that are marriage-compatible include:

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  • AA marrying AA: It is the best compatibility as a person doesn't have to worry about the genotype compatibility of their kids and posterity.
  • AA marrying AS: Lads to kids with both AA and AS, which is still on the better side. However, it could lead to kids with AS, thus limiting the partners they can marry later.

Those that shouldn't marry:

  • AS and AS partners: They should not marry as they will most likely lead to children with an SS combination.
  • AS and SS: These partners shouldn't even consider marrying or having children.
  • Finally, SS and SS are a no-go zone. They have no chance of their offsprings escaping sickle cell disease.

The genotype characteristics of a person are fundamental. This is why it is always advisable to understand the best blood group compatibility for marriage before settling down.

In a related post, shared different types of genotype and what each of them has to do with a person's blood group.

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Among other things, you will get to know how genotypes are come about and how blood types and genotypes related. What makes genotype and phenotype different is also discussed in the post.

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